You may have side effects from the chemotherapy drugs you take when also getting all-trans retinoic acid (ATRA). You could also experience retinoic acid syndrome. Within the first three weeks of treatment, this potentially fatal syndrome causes these symptoms:
Breathing problems or cough due to backup of fluid in the lungs
Low blood pressure
Irregular heart beat
Severe fluid retention
If you develop symptoms of retinoic acid syndrome, your doctor may prescribe steroids or have you stop ATRA treatment for a few days.
These are other possible side effects of ATRA. Discuss how best to manage them with your doctor or nurse:
Dry skin, dry mouth, or cracking at the corners of the mouth