Clinical trials are studies, managed by government agencies, educational institutions, private not-for-profit organizations, or commercial businesses, to develop, produce, and evaluate the effectiveness of new treatments and therapies for diseases.
BCPT was a clinical trial that studied tamoxifen as a prevention therapy for those at high risk for breast cancer. Data showed the results of tamoxifen treatment to be "highly significant," with a 49 percent reduction in the number of invasive breast cancers seen across all age groups.
STAR was a clinical trial of the drug raloxifene that included more than 19,000 postmenopausal women at increased risk for breast cancer. The results showed that raloxifene worked as well as tamoxifen at reducing breast cancer risk.